Phenotypes associated with this allele

• Allele Symbol: Col4a2^ENU4003
• Allele Name: ENU mutation 4003
• Allele ID: MGI:4822172
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Col4a2^ENU4003/Col4a2^ENU4003	C3.D2-Col4a2^ENU4003	MGI:4822374
ht2	Col4a2^ENU4003/Col4a2^+	C3.D2-Col4a2^ENU4003	MGI:4822255

Genotype
MGI:4822374

hm1

• Allelic Composition: Col4a2^ENU4003/Col4a2^ENU4003
• Genetic Background: C3.D2-Col4a2^ENU4003

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

lethality throughout fetal growth and development, complete penetrance ( J:163225 )

• reduced numbers of embryos consistent with death of all homozygotes

• no homozygotes at birth

Genotype
MGI:4822255

ht2

• Allelic Composition: Col4a2^ENU4003/Col4a2⁺
• Genetic Background: C3.D2-Col4a2^ENU4003

vision/eye

abnormal lens morphology ( J:163225 )

• total lens opacity

anterior polar cataract ( J:163225 )

buphthalmos ( J:163225 )

microphthalmia ( J:163225 )

hematopoietic system

decreased erythrocyte cell number ( J:163225 )

decreased hematocrit ( J:163225 )

decreased hemoglobin content ( J:163225 )

nervous system

abnormal brain morphology ( J:163225 )

• abnormal brain anatomy in some but not all mice

cardiovascular system

hemorrhage ( J:163225 )

• intraorbital hemorrhage