Phenotypes associated with this allele

• Allele Symbol: Col4a2^ENU4020
• Allele Name: ENU mutation 4020
• Allele ID: MGI:4822173
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Col4a2^ENU4020/Col4a2^ENU4020	C3.D2-Col4a2^ENU4020	MGI:4822375
ht2	Col4a2^ENU4020/Col4a2^+	C3.D2-Col4a2^ENU4020	MGI:4822323

Genotype
MGI:4822375

hm1

• Allelic Composition: Col4a2^ENU4020/Col4a2^ENU4020
• Genetic Background: C3.D2-Col4a2^ENU4020

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

lethality throughout fetal growth and development, complete penetrance ( J:163225 )

• reduced numbers of embryos consistent with death of all homozygotes

• no homozygotes at birth

Genotype
MGI:4822323

ht2

• Allelic Composition: Col4a2^ENU4020/Col4a2⁺
• Genetic Background: C3.D2-Col4a2^ENU4020

vision/eye

corneal-lenticular stalk ( J:163225 )

• adhesions between the cornea and the lens

lens vacuoles ( J:163225 )

abnormal lens epithelium morphology ( J:163225 )

• disorganized

anterior polar cataract ( J:163225 )

total cataract ( J:163225 )

• total lens opacity

hematopoietic system

decreased erythrocyte cell number ( J:163225 )

decreased hematocrit ( J:163225 )

decreased hemoglobin content ( J:163225 )

nervous system

abnormal brain morphology ( J:163225 )

• brain abnormalities in some but not all mice