All Phenotypes Col4a1<D456> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Col4a1^D456
radiation induced mutation D456
MGI:4822198

Summary

2 genotypes

Allelic Composition	Col4a1^D456/Col4a1^D456
Genetic Background	C3.D2-Col4a1^D456

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Col4a1^D456 mutation (1 available); any Col4a1 mutation (77 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

• reduced numbers of embryos consistent with death of all homozygotes

• no homozygotes at birth

Allelic Composition	Col4a1^D456/Col4a1⁺
Genetic Background	C3.D2-Col4a1^D456

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Col4a1^D456 mutation (1 available); any Col4a1 mutation (77 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

vision/eye

lens vacuoles ( J:163225 )

• lens vacuoles

cataract ( J:163225 )

• total lens opacity

microphthalmia ( J:163225 )

• some examples of microphthalmia

hematopoietic system

decreased erythrocyte cell number ( J:163225 )

decreased hematocrit ( J:163225 )

decreased hemoglobin content ( J:163225 )

nervous system

abnormal brain morphology ( J:163225 )

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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