Phenotypes associated with this allele

• Allele Symbol: Col4a1^D456
• Allele Name: radiation induced mutation D456
• Allele ID: MGI:4822198
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Col4a1^D456/Col4a1^D456	C3.D2-Col4a1^D456	MGI:4822372
ht2	Col4a1^D456/Col4a1^+	C3.D2-Col4a1^D456	MGI:4822250

Genotype
MGI:4822372

hm1

• Allelic Composition: Col4a1^D456/Col4a1^D456
• Genetic Background: C3.D2-Col4a1^D456

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

lethality throughout fetal growth and development, complete penetrance ( J:163225 )

• reduced numbers of embryos consistent with death of all homozygotes

• no homozygotes at birth

Genotype
MGI:4822250

ht2

• Allelic Composition: Col4a1^D456/Col4a1⁺
• Genetic Background: C3.D2-Col4a1^D456

vision/eye

lens vacuoles ( J:163225 )

• lens vacuoles

cataract ( J:163225 )

• total lens opacity

microphthalmia ( J:163225 )

• some examples of microphthalmia

hematopoietic system

decreased erythrocyte cell number ( J:163225 )

decreased hematocrit ( J:163225 )

decreased hemoglobin content ( J:163225 )

nervous system

abnormal brain morphology ( J:163225 )