Phenotypes associated with this allele

• Allele Symbol: Sorbs3^tm1Kiok
• Allele Name: targeted mutation 1, Noriyuki Kioka
• Allele ID: MGI:4822403
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Sorbs3^tm1Kiok/Sorbs3^tm1Kiok	B6.Cg-Sorbs3^tm1Kiok	MGI:4822404

Genotype
MGI:4822404

hm1

• Allelic Composition: Sorbs3^tm1Kiok/Sorbs3^tm1Kiok
• Genetic Background: B6.Cg-Sorbs3^tm1Kiok

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

cellular

abnormal cell migration ( J:162344 )

• Vinexin-null primary keratinocytes in vitro exhibited no difference in cell morphology or cell attachment to collagen I, from wild-type keratinocytes. However, they showed slower migration as evaluated by modified Boyden chamber assay and scratch assay

homeostasis/metabolism

delayed wound healing ( J:162344 )

• Full -thickness skin wounds were healed but delayed compared to control.