Analysis Tools
growth/size/body
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• significantly smaller than controls
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muscle
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• significantly more type I muscle fibers than in muscle from controls at 4 months (50% vs 37%)
• 51% type I fibers at 1 month of age while control muscles only have 18.5%
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• myoblasts in culture display fewer multinucleated myotubes than controls
• impaired ability of singly nucleated myoblasts to form larger multinucleated myotubes
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• cardiotoxin injury in gastrocnemius results in persistent degenerating fibers 11 days later when control muscles are nearly normal
• by 9-13 days after injury, muscle replacement with fibrotic connective tissue and adipose cells can be found
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• muscles with smaller myofibers
• difference in myofiber size is less in newborns
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limbs/digits/tail
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• significantly more type I muscle fibers than in muscle from controls at 4 months (50% vs 37%)
• 51% type I fibers at 1 month of age while control muscles only have 18.5%
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