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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Capn8tm1Hiso
targeted mutation 1, Hiroyuki Sorimachi
MGI:4822421
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Capn8tm1Hiso/Capn8tm1Hiso involves: C57BL/6N MGI:4822426


Genotype
MGI:4822426
hm1
Allelic
Composition		 Capn8tm1Hiso/Capn8tm1Hiso
Genetic
Background		 involves: C57BL/6N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Capn8tm1Hiso mutation (1 available); any Capn8 mutation (40 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
homeostasis/metabolism
increased susceptibility to injury ( J:163312 )
• following administration of 40% ethanol, mice exhibit enhanced gastric mucosal injuries compared with similarly treated wild-type mice
• however, granule production following ethanol administration is normal

digestive/alimentary system
digestive/alimentary phenotype ( J:163312 )
N
• under normal conditions, mice exhibit normal gastric mucosa




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
10/29/2024
MGI 6.24 		The Jackson Laboratory