All Phenotypes Crygc<M1Sbao> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Crygc^M1Sbao
mutation 1, Shimin Bao
MGI:4822430

Summary

2 genotypes

Allelic Composition	Crygc^M1Sbao/Crygc^M1Sbao
Genetic Background	involves: BALB/cJ * ICR

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Crygc^M1Sbao mutation (0 available); any Crygc mutation (13 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

Nuclear cataracts in Crygc^M1Sbao/Crygc^M1Sbao and Crygc^M1Sbao/Crygc⁺ mice

vision/eye

abnormal eye morphology ( J:163241 )

• at P8, a blank zone is observed in the equatorial zone in the entire eye unlike in wild-type mice

abnormal lens morphology ( J:163241 )

• sponge-like and vacuole-like degeneration is observed in the cortical area under the posterior lens capsule unlike in wild-type mice

• mice exhibit severe lens damage unlike wild-type mice

• at P8, polygonal epithelial cells are observed in the cortex underneath and equatorial region unlike in wild-type mice

developmental cataract ( J:163241 )

• at eye opening after birth, mice exhibit lens opacities in the nuclear region unlike wild-type mice

nuclear cataract ( J:163241 )

• at eye opening after birth, mice exhibit lens opacities in the nuclear region unlike wild-type mice

small lens ( J:163241 )

• at P8

Allelic Composition	Crygc^M1Sbao/Crygc⁺
Genetic Background	involves: BALB/cJ * ICR