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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Cd300lbtm1Toki
targeted mutation 1, Toshio Kitamura
MGI:4829592
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Cd300lbtm1Toki/Cd300lbtm1Toki B6.Cg-Cd300lbtm1Toki MGI:4829593


Genotype
MGI:4829593
hm1
Allelic
Composition		 Cd300lbtm1Toki/Cd300lbtm1Toki
Genetic
Background		 B6.Cg-Cd300lbtm1Toki
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cd300lbtm1Toki mutation (1 available); any Cd300lb mutation (24 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype

Cd300lbtm1Toki/Cd300lbtm1Toki mice were protected from renal ischemia reperfusion injury

homeostasis/metabolism
decreased susceptibility to kidney reperfusion injury ( J:163402 )
• decrease in the accumulation of neutrophils, production of cytokines, and tubular necrosis in the kidney following ischemia reperfusion injury

immune system
immune system phenotype ( J:163402 )
N
• no major differences are detected in the myeloid and lymphoid lineage development in the bone marrow , spleen, thymus, peripheral blood, or peritoneal cells

renal/urinary system
decreased susceptibility to kidney reperfusion injury ( J:163402 )
• decrease in the accumulation of neutrophils, production of cytokines, and tubular necrosis in the kidney following ischemia reperfusion injury




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory