All Phenotypes Mir451a<tm1.2Doca> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Mir451a^tm1.2Doca
targeted mutation 1.2, Donal O'Carroll
MGI:4829620

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Mir451a^tm1.2Doca/Mir451a^tm1.2Doca	involves: 129P2/OlaHsd * 129S4/SvJaeSor * BALB/cJ	MGI:4829627

Allelic Composition	Mir451a^tm1.2Doca/Mir451a^tm1.2Doca
Genetic Background	involves: 129P2/OlaHsd * 129S4/SvJaeSor * BALB/cJ

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mir451a^tm1.2Doca mutation (1 available); any Mir451a mutation (4 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

hematopoietic system

abnormal hematopoietic system morphology/development ( J:163418 )

• authors state that mice exhibit a largely indistinguishable phenotype from Mir144/Mir451^tm1.2Doca homozygotes

enlarged spleen ( J:163418 )

increased erythroid progenitor cell number ( J:163418 )

• in the spleen

decreased erythrocyte cell number ( J:163418 )

decreased hematocrit ( J:163418 )

increased red blood cell distribution width ( J:163418 )

immune system

enlarged spleen ( J:163418 )

growth/size/body

enlarged spleen ( J:163418 )

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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