All Phenotypes Rnf4<Gt(ROSABetageo)1Gel> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Rnf4^{Gt(ROSABetageo)1Gel}
gene trap 1, Gary E Lyons
MGI:4829855

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Rnf4^{Gt(ROSABetageo)1Gel}/Rnf4^{Gt(ROSABetageo)1Gel}	involves: 129S1/Sv * 129X1/SvJ	MGI:4829856

Allelic Composition	Rnf4^{Gt(ROSABetageo)1Gel}/Rnf4^{Gt(ROSABetageo)1Gel}
Genetic Background	involves: 129S1/Sv * 129X1/SvJ

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Rnf4^{Gt(ROSABetageo)1Gel} mutation (1 available); any Rnf4 mutation (22 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

lethality throughout fetal growth and development, complete penetrance ( J:163687 )

• die between E14 and E15

cardiovascular system

ventricular septal defect ( J:163687 )

abnormal cardiovascular system physiology ( J:163687 )

• cardiac insufficiency

cellular

abnormal DNA methylation ( J:163687 )

• global DNA hypermethylation is seen in MEFs

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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