Phenotypes associated with this allele

• Allele Symbol: Esr1^tm1.1Pws
• Allele Name: targeted mutation 1.1, Philip W Shaul
• Allele ID: MGI:4829939
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Esr1^tm1.1Pws/Esr1^tm1.1Pws	involves: C57BL/6 * CBA	MGI:4829961

Genotype
MGI:4829961

hm1

• Allelic Composition: Esr1^tm1.1Pws/Esr1^tm1.1Pws
• Genetic Background: involves: C57BL/6 * CBA

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

reproductive system

abnormal reproductive system morphology ( J:163783 )

• authors state that mice exhibit similar reproductive phenotypes observed in Esr1^tm1.1Mma homozygotes

cardiovascular system

abnormal vascular wound healing ( J:163783 )

• following arterial denudation, mice exhibit decreased estrogen and estrogen-dendrimer conjugate (EDC)-stimulated reendothelialization compared with similarly treated wild-type mice

homeostasis/metabolism

abnormal vascular wound healing ( J:163783 )

• following arterial denudation, mice exhibit decreased estrogen and estrogen-dendrimer conjugate (EDC)-stimulated reendothelialization compared with similarly treated wild-type mice