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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Cecr2tm1.1Hemc
targeted mutation 1.1, Heather E McDermid
MGI:4829945
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Cecr2tm1.1Hemc/Cecr2tm1.1Hemc involves: 129S6/SvEvTac * BALB/c * C57BL/6NTac MGI:4829946
hm2
 		Cecr2tm1.1Hemc/Cecr2tm1.1Hemc involves: 129S6/SvEvTac * C57BL/6NTac * FVB/N MGI:4829947


Genotype
MGI:4829946
hm1
Allelic
Composition		 Cecr2tm1.1Hemc/Cecr2tm1.1Hemc
Genetic
Background		 involves: 129S6/SvEvTac * BALB/c * C57BL/6NTac
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cecr2tm1.1Hemc mutation (2 available); any Cecr2 mutation (91 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
exencephaly ( J:163648 )
• with 96% penetrance




Genotype
MGI:4829947
hm2
Allelic
Composition		 Cecr2tm1.1Hemc/Cecr2tm1.1Hemc
Genetic
Background		 involves: 129S6/SvEvTac * C57BL/6NTac * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cecr2tm1.1Hemc mutation (2 available); any Cecr2 mutation (91 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
premature death ( J:163648 )
• lethal within the first few days of undetermined cause

nervous system
exencephaly ( J:163648 )
• with 31% penetrance
encephalomeningocele ( J:163648 )
• forebrain encephalocele

craniofacial

growth/size/body
midline facial cleft ( J:163648 )




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory