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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Rr103tm3Sia
targeted mutation 3, Shinichi Aizawa
MGI:4830691
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
cx1
 		Rr103tm3Sia/Rr103tm3Sia
Otx2tm1Sia/Otx2+ 		involves: C57BL/6 * CBA MGI:4830713
cx2
 		Emx1tm1Sia/Emx1tm1Sia
Rr103tm3Sia/Rr103tm3Sia 		involves: C57BL/6 * CBA MGI:4830714


Genotype
MGI:4830713
cx1
Allelic
Composition		 Rr103tm3Sia/Rr103tm3Sia
Otx2tm1Sia/Otx2+
Genetic
Background		 involves: C57BL/6 * CBA
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Otx2tm1Sia mutation (1 available); any Otx2 mutation (50 available)
Rr103tm3Sia mutation (0 available); any Rr103 mutation (0 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
absent diencephalon ( J:163926 )
• at E8.5, mice exhibit a loss of diencephalic structures compared with wild-type mice




Genotype
MGI:4830714
cx2
Allelic
Composition		 Emx1tm1Sia/Emx1tm1Sia
Rr103tm3Sia/Rr103tm3Sia
Genetic
Background		 involves: C57BL/6 * CBA
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Emx1tm1Sia mutation (1 available); any Emx1 mutation (34 available)
Rr103tm3Sia mutation (0 available); any Rr103 mutation (0 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
abnormal pallium development ( J:163926 )
• mice exhibit a moderate loss of the medial pallium compared with wild-type mice
abnormal cerebral cortex morphology ( J:163926 )
• mice exhibit moderately defective cortical lamination compared with wild-type mice
• however, mice exhibit normal ganglionic eminences




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory