About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Cd44tm2.1Ugu
targeted mutation 2.1, Ursula Gunthert
MGI:4835490
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Cd44tm2.1Ugu/Cd44tm2.1Ugu B6.129-Cd44tm2.1Ugu MGI:4843550


Genotype
MGI:4843550
hm1
Allelic
Composition		 Cd44tm2.1Ugu/Cd44tm2.1Ugu
Genetic
Background		 B6.129-Cd44tm2.1Ugu
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cd44tm2.1Ugu mutation (7 available); any Cd44 mutation (72 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
decreased T cell proliferation ( J:199279 )
• of lymph node T cells repeatedly stimulated with MOG35-55
decreased susceptibility to experimental autoimmune encephalomyelitis ( J:199279 )
• with reduced symptoms, fewer inflammatory infiltrates and increased apoptotic activity

hematopoietic system
decreased T cell proliferation ( J:199279 )
• of lymph node T cells repeatedly stimulated with MOG35-55

cellular
decreased T cell proliferation ( J:199279 )
• of lymph node T cells repeatedly stimulated with MOG35-55




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/05/2024
MGI 6.24 		The Jackson Laboratory