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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Grhl3tm2.1Jane
targeted mutation 2.1, Stephen M Jane
MGI:4836382
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Grhl3tm2.1Jane/Grhl3tm2.1Jane involves: 129S1/Sv * BALB/cJ MGI:4836391
ht2
 		Grhl3tm1Jane/Grhl3tm2.1Jane involves: 129S1/Sv * BALB/cJ MGI:4836393


Genotype
MGI:4836391
hm1
Allelic
Composition		 Grhl3tm2.1Jane/Grhl3tm2.1Jane
Genetic
Background		 involves: 129S1/Sv * BALB/cJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Grhl3tm2.1Jane mutation (1 available); any Grhl3 mutation (53 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging

nervous system
spina bifida ( J:164805 )
• in the lumbo-sacral region in almost all embryos

embryo
spina bifida ( J:164805 )
• in the lumbo-sacral region in almost all embryos




Genotype
MGI:4836393
ht2
Allelic
Composition		 Grhl3tm1Jane/Grhl3tm2.1Jane
Genetic
Background		 involves: 129S1/Sv * BALB/cJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Grhl3tm1Jane mutation (1 available); any Grhl3 mutation (53 available)
Grhl3tm2.1Jane mutation (1 available); any Grhl3 mutation (53 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging

nervous system
spina bifida ( J:164805 )
• in the lumbo-sacral region in almost all embryos

embryo
spina bifida ( J:164805 )
• in the lumbo-sacral region in almost all embryos




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory