All Phenotypes Nedd4<tm3.1Bros> MGI Mouse

About Help FAQ

Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Nedd4^tm3.1Bros
targeted mutation 3.1, Nils Brose
MGI:4836405

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
cn1	Nedd4^tm3.1Bros/Nedd4^tm3.1Bros Neurod6^tm1(cre)Kan/Neurod6⁺	involves: 129 * C57BL/6 * C57BL/6N * SJL	MGI:4836485

Allelic Composition	Nedd4^tm3.1Bros/Nedd4^tm3.1Bros Neurod6^tm1(cre)Kan/Neurod6⁺
Genetic Background	involves: 129 * C57BL/6 * C57BL/6N * SJL

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nedd4^tm3.1Bros mutation (0 available); any Nedd4 mutation (116 available)
Neurod6^tm1(cre)Kan mutation (0 available); any Neurod6 mutation (18 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

nervous system

nervous system phenotype ( J:164745 )

N	• cerebellum size is normal

abnormal cerebral hemisphere morphology ( J:164745 )

• small

thin cerebral cortex ( J:164745 )

abnormal dendrite morphology ( J:164745 )

• dendrite extent and branching on CA1 region neurons are reduced compared to in wild-type mice

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/12/2024 MGI 6.24