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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Pkd1l3tm1.1Abek
targeted mutation 1.1, Keiko Abe
MGI:4837113
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Pkd1l3tm1.1Abek/Pkd1l3tm1.1Abek involves: 129S/SvEv * C57BL/6 MGI:4837115
cx2
 		Pkd1l3tm1.1Abek/Pkd1l3tm1.1Abek
Pkd2l1tm1.1Yuni/Pkd2l1tm1.1Yuni 		involves: 129S/SvEv * C57BL/6 * CBA MGI:5008626


Genotype
MGI:4837115
hm1
Allelic
Composition		 Pkd1l3tm1.1Abek/Pkd1l3tm1.1Abek
Genetic
Background		 involves: 129S/SvEv * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Pkd1l3tm1.1Abek mutation (1 available); any Pkd1l3 mutation (154 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
nervous system phenotype ( J:172581 )
N
• mice exhibit normal nerve response to sour tastants

taste/olfaction
taste/olfaction phenotype ( J:172581 )
N
• mice exhibit normal nerve response to sour tastants




Genotype
MGI:5008626
cx2
Allelic
Composition		 Pkd1l3tm1.1Abek/Pkd1l3tm1.1Abek
Pkd2l1tm1.1Yuni/Pkd2l1tm1.1Yuni
Genetic
Background		 involves: 129S/SvEv * C57BL/6 * CBA
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Pkd1l3tm1.1Abek mutation (1 available); any Pkd1l3 mutation (154 available)
Pkd2l1tm1.1Yuni mutation (1 available); any Pkd2l1 mutation (50 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
abnormal nerve fiber response ( J:172581 )
• chorda tympani (CT) nerves response to sour tastants is lower than in wild-type mice
• however, mice exhibit normal CT nerve response to sweet, salty, bitter, and umami compounds and glossopharyngeal nerve response to all tastants

taste/olfaction
abnormal gustatory system physiology ( J:172581 )
• chorda tympani (CT) nerves response to sour tastants is lower than in wild-type mice
• however, mice exhibit normal CT nerve response to sweet, salty, bitter, and umami compounds and glossopharyngeal nerve response to all tastants




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory