Phenotypes associated with this allele

• Allele Symbol: Cebpa^tm1Timc
• Allele Name: targeted mutation 1, Nikolai A Timchenko
• Allele ID: MGI:4837200
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Cebpa^tm1Timc/Cebpa^tm1Timc	Not Specified	MGI:4837203

Genotype
MGI:4837203

hm1

• Allelic Composition: Cebpa^tm1Timc/Cebpa^tm1Timc
• Genetic Background: Not Specified

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

homeostasis/metabolism

decreased circulating glucose level ( J:163725 )

increased circulating triglyceride level ( J:163725 )

increased circulating alanine transaminase level ( J:163725 )

increased circulating aspartate transaminase level ( J:163725 )

increased incidence of tumors by chemical induction ( J:163725 )

• earlier development of tumors in response to diethylnitrosamine phenobarbital induced tumors

liver/biliary system

decreased hepatocyte proliferation ( J:163725 )

hepatic steatosis ( J:163725 )

• leads to the accumulation of fat droplets in the livers at a very early age

neoplasm

increased incidence of tumors by chemical induction ( J:163725 )

• earlier development of tumors in response to diethylnitrosamine phenobarbital induced tumors

cellular

decreased hepatocyte proliferation ( J:163725 )