Analysis Tools
mortality/aging
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• following withdrawal of doxycycline
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cardiovascular system
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• after doxycycline withdrawal, mice exhibit a trend towards increased inflammation in the atrioventricular node unlike wild-type mice
• however, there is no evidence of fibrosis, calcification, or necrosis
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• mild following withdrawal of doxycycline
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• at 15 to 30 weeks after doxycycline withdrawal, mice with congestive heart failure exhibit increase chamber sizes compared with wild-type mice
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• following withdrawal of doxycycline
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• 30 days following the withdrawal of doxycycline, mice exhibit increased left ventricular end-diastolic dimension compared with wild-type mice
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• following withdrawal of doxycycline
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• following withdrawal of doxycycline
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• at 15 to 30 weeks after doxycycline withdrawal in mice with congestive heart failure
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• at 15 to 30 weeks after doxycycline withdrawal, mice with congestive heart failure exhibit depressed hemodynamics compared with wild-type mice
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• infrequently after doxycycline withdrawal
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• after doxycycline withdrawal, mice exhibit sudden cardiac death associated with cardiac asystole preceded by a short burst of 2:1 block unlike wild-type mice
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• after doxycycline withdrawal, mice exhibit bifid P waves with elongation of P-wave duration unlike wild-type mice
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heart block
(
J:132082
)
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• progressive after doxycycline withdrawal
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• after doxycycline withdrawal, 4 mice exhibit atrioventricular block with Wenckebach periodicity (i.e. progressive elongation of PR interval followed by dropped ventricular beats) unlike wild-type mice
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• after doxycycline withdrawal
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• after doxycycline withdrawal
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• in 6 of 78 mice 15 to 30 weeks after doxycycline withdrawal
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• mild following withdrawal of doxycycline
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growth/size/body
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• at 15 to 30 weeks after doxycycline withdrawal, mice with congestive heart failure exhibit increase chamber sizes compared with wild-type mice
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• following withdrawal of doxycycline
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• at 15 to 30 weeks after doxycycline withdrawal in mice with congestive heart failure
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homeostasis/metabolism
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• at 15 to 30 weeks after doxycycline withdrawal in mice with congestive heart failure
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immune system
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• mild following withdrawal of doxycycline
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behavior/neurological
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• at 15 to 30 weeks after doxycycline withdrawal in mice with congestive heart failure
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respiratory system
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• at 15 to 30 weeks after doxycycline withdrawal in mice with congestive heart failure
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muscle
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• after doxycycline withdrawal, mice exhibit a trend towards increased inflammation in the atrioventricular node unlike wild-type mice
• however, there is no evidence of fibrosis, calcification, or necrosis
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• mild following withdrawal of doxycycline
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cellular
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• at 15 to 30 weeks after doxycycline withdrawal in mice with congestive heart failure
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