Phenotypes associated with this allele

• Allele Symbol: Atp8a2^agil-3J
• Allele Name: agitans-like 3 Jackson
• Allele ID: MGI:4837728
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Atp8a2^agil-3J/Atp8a2^agil-3J	CBA/J-Atp8a2^agil-3J/GrsrJ	MGI:5292110

Genotype
MGI:5292110

hm1

• Allelic Composition: Atp8a2^agil-3J/Atp8a2^agil-3J
• Genetic Background: CBA/J-Atp8a2^agil-3J/GrsrJ

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

ataxia ( J:176491 )

• by 2 weeks of age homozygotes have a wobbling gait with retraction of the back legs into the body with picked up by the tail

mortality/aging

postnatal lethality ( J:176491 )

• most homozygotes do not live to adulthood

growth/size/body

postnatal growth retardation ( J:176491 )

nervous system

abnormal spinal cord white matter morphology ( J:176491 )

• 1 of 2 homozygotes assessed histologically showed mild degeneration of white matter in the spinal cord

axonal dystrophy ( J:176491 )

• 1 of 2 homozygotes assessed histologically showed axonal dystrophy

digestive/alimentary system

abnormal enterocyte morphology ( J:176491 )

• 1 of 2 homozygotes assessed histologically was found to have atrophic enterocytes in the small intestine

endocrine/exocrine glands

pancreas necrosis ( J:176491 )

• 1 of 2 homozygotes assessed histologically showed focal necrosis in the pancreas