hematopoietic system
N |
• proportions of B and T lymphocytes, monocytes and macrophage are about normal
• developmental stages of lymphocytes are present in expected numbers
|
• decreased number of B220 cells in the spleen
|
• decreased surface expression of IgM on bone marrow B220 cells
|
immune system
N |
• cell numbers in the spleen are normal
• no effect on class switch recombination
• antigen activation of B cells is normal
|
• decreased number of B220 cells in the spleen
|
• decreased surface expression of IgM on bone marrow B220 cells
|