About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Fbn1tm2.1Lysa
targeted mutation 2.1, Lynn Y Sakai
MGI:4839071
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Fbn1tm2.1Lysa/Fbn1tm2.1Lysa involves: C57BL/6 MGI:4839091


Genotype
MGI:4839091
hm1
Allelic
Composition		 Fbn1tm2.1Lysa/Fbn1tm2.1Lysa
Genetic
Background		 involves: C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Fbn1tm2.1Lysa mutation (0 available); any Fbn1 mutation (173 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
mortality/aging ( J:165897 )
N
• mice exhibit normal lifespan unlike mice homozygous for other Fbn1 mutations

cardiovascular system
cardiovascular system phenotype ( J:165897 )
N
• aortic elastic fiber morphology is normal

integument
integument phenotype ( J:165897 )
N
• mice exhibit normal cutaneous microfibril morphology




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory