Phenotypes associated with this allele

• Allele Symbol: Otud7b^{tm1(NCOM)Cmhd}
• Allele Name: targeted mutation 1, Centre for Modelling Human Disease
• Allele ID: MGI:4839147
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Otud7b^tm1(NCOM)Cmhd/Otud7b^tm1(NCOM)Cmhd	C57BL/6N-Otud7b^tm1(NCOM)Cmhd/Tcp	MGI:5782151
hm2	Otud7b^tm1(NCOM)Cmhd/Otud7b^tm1(NCOM)Cmhd	involves: C57BL/6N	MGI:5568495

Genotype
MGI:5782151

hm1

• Allelic Composition: Otud7b^{tm1(NCOM)Cmhd}/Otud7b^{tm1(NCOM)Cmhd}
• Genetic Background: C57BL/6N-Otud7b^{tm1(NCOM)Cmhd}/Tcp
• Cell Lines: N00135P0_C_22T_G9

Data Sources

IMPC Data for Otud7b

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

growth/size/body

decreased body weight ( J:165965 )

IMPC - CMHD

homeostasis/metabolism

decreased circulating cholesterol level ( J:165965 )

♀

IMPC - CMHD

Genotype
MGI:5568495

hm2

• Allelic Composition: Otud7b^{tm1(NCOM)Cmhd}/Otud7b^{tm1(NCOM)Cmhd}
• Genetic Background: involves: C57BL/6N

hematopoietic system

abnormal granulocyte physiology ( J:209709 )

• increased tissue accumulation of granulocytes in kidneys in response to renal ischemia and reperfusion

immune system

abnormal granulocyte physiology ( J:209709 )

• increased tissue accumulation of granulocytes in kidneys in response to renal ischemia and reperfusion