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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Med12tm1.2Hsch
targeted mutation 1.2, Heinrich Schrewe
MGI:4839486
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
ot1
 		Med12tm1.2Hsch/Y chimera involves: 129S6/SvEvTac * C57BL/6NCr MGI:4839516


Genotype
MGI:4839516
ot1
Allelic
Composition		 Med12tm1.2Hsch/Y
Genetic
Background		 chimera involves: 129S6/SvEvTac * C57BL/6NCr
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Med12tm1.2Hsch mutation (0 available); any Med12 mutation (6 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
embryonic lethality between implantation and somite formation, complete penetrance ( J:166040 )
• embryos resulting from tetraploid complementation rescue do not reach head fold stage
• arrested at E7.5

embryo
absent anterior visceral endoderm ( J:166040 )
• anterior visceral endoderm is absent in embryos resulting from tetraploid complementation rescue




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory