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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Tg(Thy1-APPSwe)71Jgr
transgene insertion 71, J Richards
MGI:4839764
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cx1
 		Tg(Prnp-PSEN2*N141I)30Jgr/0
Tg(Thy1-APPSwe)71Jgr/0 		B6.Cg-Tg(Prnp-PSEN2*N141I)30Jgr Tg(Thy1-APPSwe)71Jgr MGI:4839774


Genotype
MGI:4839774
cx1
Allelic
Composition		 Tg(Prnp-PSEN2*N141I)30Jgr/0
Tg(Thy1-APPSwe)71Jgr/0
Genetic
Background		 B6.Cg-Tg(Prnp-PSEN2*N141I)30Jgr Tg(Thy1-APPSwe)71Jgr
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
nervous system phenotype ( J:165986 )
N
• mice exhibit normal LTP
abnormal neuron differentiation ( J:165986 )
• at 4 weeks, mice exhibit a decrease in the number of surviving CldU+ cells in the dentate gyrus compared with wild-type mice
• however, proliferation of neuronal progenitors is normal

cellular
abnormal neuron differentiation ( J:165986 )
• at 4 weeks, mice exhibit a decrease in the number of surviving CldU+ cells in the dentate gyrus compared with wild-type mice
• however, proliferation of neuronal progenitors is normal




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory