About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Tg(Prnp-PSEN2*N141I)30Jgr
transgene insertion 30, J Richards
MGI:4839766
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cx1
 		Tg(Prnp-PSEN2*N141I)30Jgr/0
Tg(Thy1-APPSwe)71Jgr/0 		B6.Cg-Tg(Prnp-PSEN2*N141I)30Jgr Tg(Thy1-APPSwe)71Jgr MGI:4839774


Genotype
MGI:4839774
cx1
Allelic
Composition		 Tg(Prnp-PSEN2*N141I)30Jgr/0
Tg(Thy1-APPSwe)71Jgr/0
Genetic
Background		 B6.Cg-Tg(Prnp-PSEN2*N141I)30Jgr Tg(Thy1-APPSwe)71Jgr
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
nervous system phenotype ( J:165986 )
N
• mice exhibit normal LTP
abnormal neuron differentiation ( J:165986 )
• at 4 weeks, mice exhibit a decrease in the number of surviving CldU+ cells in the dentate gyrus compared with wild-type mice
• however, proliferation of neuronal progenitors is normal

cellular
abnormal neuron differentiation ( J:165986 )
• at 4 weeks, mice exhibit a decrease in the number of surviving CldU+ cells in the dentate gyrus compared with wild-type mice
• however, proliferation of neuronal progenitors is normal




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory