homeostasis/metabolism
• during the dark phase
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• mice treated with leptin fail to exhibit a decrease in food intake unlike similarly treated wild-type mice
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adipose tissue
• mice exhibit increased omental, mesenteric, and subcutaneous adipose weight compared with wild-type mice
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behavior/neurological
• during the dark
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growth/size/body
• mice exhibit increased body weight compared with wild-type mice and Leprdb homozygotes
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liver/biliary system