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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Leprm5Btlr
mutation 5, Bruce Beutler
MGI:4839995
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Leprm5Btlr/Leprm5Btlr C57BL/6-Leprm5Btlr MGI:4840002


Genotype
MGI:4840002
hm1
Allelic
Composition
Leprm5Btlr/Leprm5Btlr
Genetic
Background
C57BL/6-Leprm5Btlr
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Leprm5Btlr mutation (0 available); any Lepr mutation (122 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
homeostasis/metabolism
• mice treated with leptin fail to exhibit a decrease in food intake unlike similarly treated wild-type mice

adipose tissue
• mice exhibit increased omental, mesenteric, and subcutaneous adipose weight compared with wild-type mice

behavior/neurological
• during the dark

growth/size/body
• mice exhibit increased body weight compared with wild-type mice and Leprdb homozygotes
• on normal chow

liver/biliary system





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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
10/29/2024
MGI 6.24
The Jackson Laboratory