Phenotypes associated with this allele

• Allele Symbol: Spink14^{tm1e(KOMP)Wtsi}
• Allele Name: targeted mutation 1e, Wellcome Trust Sanger Institute
• Allele ID: MGI:4841420
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Spink14^tm1e(KOMP)Wtsi/Spink14^tm1e(KOMP)Wtsi	C57BL/6N-Spink14^tm1e(KOMP)Wtsi/Wtsi	MGI:5757761

Genotype
MGI:5757761

hm1

• Allelic Composition: Spink14^{tm1e(KOMP)Wtsi}/Spink14^{tm1e(KOMP)Wtsi}
• Genetic Background: C57BL/6N-Spink14^{tm1e(KOMP)Wtsi}/Wtsi
• Cell Lines: EPD0652_1_D10

Data Sources

IMPC Data for Spink14

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

growth/size/body

increased lean body mass ( J:211773 )

♂

IMPC - WTSI

hematopoietic system

increased memory-marker NK cell number ( J:211773 )

IMPC - WTSI

decreased NK cell number ( J:211773 )

IMPC - WTSI

decreased immature NK cell number ( J:211773 )

IMPC - WTSI

decreased mature NK cell number ( J:211773 )

IMPC - WTSI

decreased macrophage cell number ( J:211773 )

IMPC - WTSI

immune system

increased memory-marker NK cell number ( J:211773 )

IMPC - WTSI

decreased NK cell number ( J:211773 )

IMPC - WTSI

decreased immature NK cell number ( J:211773 )

IMPC - WTSI

decreased mature NK cell number ( J:211773 )

IMPC - WTSI

decreased macrophage cell number ( J:211773 )

IMPC - WTSI

increased anti-nuclear antigen antibody level ( J:211773 )

IMPC - WTSI

skeleton

increased bone mineral density ( J:211773 )

IMPC - WTSI