All Phenotypes Mta1<tm1a(EUCOMM)Wtsi> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Mta1^{tm1a(EUCOMM)Wtsi}
targeted mutation 1a, Wellcome Trust Sanger Institute
MGI:4842891

Summary

3 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Mta1^{tm1a(EUCOMM)Wtsi}/Mta1^{tm1a(EUCOMM)Wtsi}	129S/SvEvBrd-Mta1^{tm1a(EUCOMM)Wtsi}/WtsiH	MGI:5781674
hm2	Mta1^{tm1a(EUCOMM)Wtsi}/Mta1^{tm1a(EUCOMM)Wtsi}	involves: 129S7/SvEvBrd	MGI:6358202
ht3	Mta1^{tm1a(EUCOMM)Wtsi}/Mta1⁺	129S/SvEvBrd-Mta1^{tm1a(EUCOMM)Wtsi}/WtsiH	MGI:5781673

Allelic Composition	Mta1^{tm1a(EUCOMM)Wtsi}/Mta1^{tm1a(EUCOMM)Wtsi}
Genetic Background	129S/SvEvBrd-Mta1^{tm1a(EUCOMM)Wtsi}/WtsiH
Cell Lines	EPD0002_2_B07

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mta1^{tm1a(EUCOMM)Wtsi} mutation (2 available); any Mta1 mutation (83 available)

Data Sources

IMPC Data for Mta1

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

behavior/neurological

abnormal behavior ( J:175295 )

IMPC - WTSI

hematopoietic system

thrombocytopenia ( J:175295 )

IMPC - WTSI

homeostasis/metabolism

decreased circulating LDL cholesterol level ( J:175295 )

IMPC - WTSI

limbs/digits/tail

decreased caudal vertebrae number ( J:175295 )

IMPC - WTSI

skeleton

decreased caudal vertebrae number ( J:175295 )

IMPC - WTSI

decreased lumbar vertebrae number ( J:175295 )

IMPC - WTSI

increased sacral vertebrae number ( J:175295 )

IMPC - WTSI

abnormal bone mineralization ( J:175295 )

IMPC - WTSI

growth/size/body

decreased body weight ( J:165965 )

IMPC - WTSI

Allelic Composition	Mta1^{tm1a(EUCOMM)Wtsi}/Mta1^{tm1a(EUCOMM)Wtsi}
Genetic Background	involves: 129S7/SvEvBrd

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mta1^{tm1a(EUCOMM)Wtsi} mutation (2 available); any Mta1 mutation (83 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

mortality/aging ( J:278486 )

N	• mice are viable

Allelic Composition	Mta1^{tm1a(EUCOMM)Wtsi}/Mta1⁺
Genetic Background	129S/SvEvBrd-Mta1^{tm1a(EUCOMM)Wtsi}/WtsiH
Cell Lines	EPD0002_2_B07

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mta1^{tm1a(EUCOMM)Wtsi} mutation (2 available); any Mta1 mutation (83 available)

Data Sources

IMPC Data for Mta1

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

homeostasis/metabolism

increased circulating triglyceride level ( J:175295 )

IMPC - WTSI

limbs/digits/tail

decreased caudal vertebrae number ( J:175295 )

IMPC - WTSI

skeleton

decreased caudal vertebrae number ( J:175295 )

IMPC - WTSI

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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