Analysis Tools
mortality/aging
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• all homozygotes die in utero prior to E16.5; however, viable embryos are still detected at E14.5
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growth/size/body
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• smaller size in a dead embryo at E16.5
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• homozygotes display growth retardation at E14.5
• lack of proper organ development in a dead embryo at E16.5
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limbs/digits/tail
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• homozygotes display delayed limb development at E13.5
• lack of proper limbs in a dead embryo at E16.5
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cardiovascular system
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• lack of proper blood vessels in a dead embryo at E16.5
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