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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Klk7tm1(KOMP)Vlcg
targeted mutation 1, Velocigene
MGI:4843047
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Klk7tm1(KOMP)Vlcg/Klk7tm1(KOMP)Vlcg involves: C57BL/6NTac MGI:6160917
cx2
 		Apptm3.1Tcs/Apptm3.1Tcs
Klk7tm1(KOMP)Vlcg/Klk7tm1(KOMP)Vlcg 		involves: C57BL/6NTac MGI:6160918


Genotype
MGI:6160917
hm1
Allelic
Composition		 Klk7tm1(KOMP)Vlcg/Klk7tm1(KOMP)Vlcg
Genetic
Background		 involves: C57BL/6NTac
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Klk7tm1(KOMP)Vlcg mutation (1 available); any Klk7 mutation (13 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
normal phenotype
no abnormal phenotype detected ( J:261970 )
• normal and were fertile




Genotype
MGI:6160918
cx2
Allelic
Composition		 Apptm3.1Tcs/Apptm3.1Tcs
Klk7tm1(KOMP)Vlcg/Klk7tm1(KOMP)Vlcg
Genetic
Background		 involves: C57BL/6NTac
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Apptm3.1Tcs mutation (2 available); any App mutation (105 available)
Klk7tm1(KOMP)Vlcg mutation (1 available); any Klk7 mutation (13 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
amyloid beta deposits ( J:261970 )
• increased 5.6-fold compared with Apptm3.1Tcs homozygotes

homeostasis/metabolism
amyloid beta deposits ( J:261970 )
• increased 5.6-fold compared with Apptm3.1Tcs homozygotes




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory