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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Pkd2tm1.2Tjwt
targeted mutation 1.2, Terry J Watnick
MGI:4843127
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Pkd2tm1.2Tjwt/Pkd2tm1.2Tjwt involves: 129S/Sv * 129X1/SvJ * C57BL/6 * SJL MGI:4843163
cn2
 		Pkd2tm1.1Tjwt/Pkd2tm1.2Tjwt
Meox2tm1(cre)Sor/Meox2+ 		involves: 129S/Sv * 129X1/SvJ * C57BL/6 * SJL MGI:4843164


Genotype
MGI:4843163
hm1
Allelic
Composition		 Pkd2tm1.2Tjwt/Pkd2tm1.2Tjwt
Genetic
Background		 involves: 129S/Sv * 129X1/SvJ * C57BL/6 * SJL
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Pkd2tm1.2Tjwt mutation (0 available); any Pkd2 mutation (85 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
lethality throughout fetal growth and development, complete penetrance ( J:165114 )
• mice die between E15.5 and E19.5; none are recovered at birth




Genotype
MGI:4843164
cn2
Allelic
Composition		 Pkd2tm1.1Tjwt/Pkd2tm1.2Tjwt
Meox2tm1(cre)Sor/Meox2+
Genetic
Background		 involves: 129S/Sv * 129X1/SvJ * C57BL/6 * SJL
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Meox2tm1(cre)Sor mutation (3 available); any Meox2 mutation (18 available)
Pkd2tm1.1Tjwt mutation (1 available); any Pkd2 mutation (85 available)
Pkd2tm1.2Tjwt mutation (0 available); any Pkd2 mutation (85 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging

endocrine/exocrine glands

cardiovascular system

homeostasis/metabolism
edema ( J:165114 )
• in neonates

growth/size/body
pancreas cyst ( J:165114 )
kidney cyst ( J:165114 )
situs inversus ( J:165114 )

renal/urinary system




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
07/05/2024
MGI 6.24 		The Jackson Laboratory