Phenotypes associated with this allele

• Allele Symbol: Ptcra^tm1.1Shoy
• Allele Name: targeted mutation 1.1, Sho Yamasaki
• Allele ID: MGI:4843449
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Ptcra^tm1.1Shoy/Ptcra^tm1.1Shoy	involves: C57BL/6	MGI:4843456

Genotype
MGI:4843456

hm1

• Allelic Composition: Ptcra^tm1.1Shoy/Ptcra^tm1.1Shoy
• Genetic Background: involves: C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

immune system

decreased T cell number ( J:166147 )

• reduced alpha-beta T cell numbers in neonates but ratios are back to normal in adults

decreased thymocyte number ( J:166147 )

• significant reduction in thymocyte numbers

decreased double-positive T cell number ( J:166147 )

• reduced number of double positive thymocytes but not double negative thymocytes

• percentage of double positive thymocytes is also somewhat reduced

increased T cell number ( J:166147 )

increased DN3 thymocyte number ( J:166147 )

• significant accumulation

increased gamma-delta T cell number ( J:166147 )

• significantly increased

hematopoietic system

decreased T cell number ( J:166147 )

• reduced alpha-beta T cell numbers in neonates but ratios are back to normal in adults

decreased thymocyte number ( J:166147 )

• significant reduction in thymocyte numbers

decreased double-positive T cell number ( J:166147 )

• reduced number of double positive thymocytes but not double negative thymocytes

• percentage of double positive thymocytes is also somewhat reduced

increased T cell number ( J:166147 )

increased DN3 thymocyte number ( J:166147 )

• significant accumulation

increased gamma-delta T cell number ( J:166147 )

• significantly increased

endocrine/exocrine glands

decreased thymocyte number ( J:166147 )

• significant reduction in thymocyte numbers

increased DN3 thymocyte number ( J:166147 )

• significant accumulation