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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Glstm1a(KOMP)Mbp
targeted mutation 1a, Mouse Biology Program, UC Davis
MGI:4843620
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Glstm1a(KOMP)Mbp/Glstm1a(KOMP)Mbp involves: C57BL/6N MGI:6151065


Genotype
MGI:6151065
hm1
Allelic
Composition		 Glstm1a(KOMP)Mbp/Glstm1a(KOMP)Mbp
Genetic
Background		 involves: C57BL/6N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Glstm1a(KOMP)Mbp mutation (0 available); any Gls mutation (44 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
abnormal astrocyte morphology ( J:241505 )
• TNFA-stimulated astrocytes from E18.5 embryos exhibit a 10-fold reduction in extracellular vesicles compared with a 2-fold increase stimulated wild-type cells

cellular
cellular phenotype ( J:241505 )
N
• TNFA-stimulated astrocytes from E18.5 embryos exhibit normal reactive oxygen species production




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory