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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Tg(Trhr-EGFP)HU193Gsat
transgene insertion HU193, GENSAT Project at Rockefeller University
MGI:4847508
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cx1
 		Sema6aGt(KST069)Byg/Sema6aGt(KST069)Byg
Tg(Trhr-EGFP)HU193Gsat/0 		involves: 129P2/OlaHsd * FVB/NTac MGI:5562539


Genotype
MGI:5562539
cx1
Allelic
Composition		 Sema6aGt(KST069)Byg/Sema6aGt(KST069)Byg
Tg(Trhr-EGFP)HU193Gsat/0
Genetic
Background		 involves: 129P2/OlaHsd * FVB/NTac
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Sema6aGt(KST069)Byg mutation (1 available); any Sema6a mutation (85 available)
Tg(Trhr-EGFP)HU193Gsat mutation (1 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
abnormal single cell response ( J:202884 )
• cell patch recording of direction-selective ganglion cells presented with drifting-bar motion stimulation show that On direction-selective tuning is compromised; however, Off response is similar to controls
• On responses have abnormal, broader, directional tuning, with the magnitudes of the response vector sums being significantly lower




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory