Phenotypes associated with this allele

• Allele Symbol: Ahi1^tm1Xjl
• Allele Name: targeted mutation 1, Xiao-Jiang Li
• Allele ID: MGI:4849287
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
cn1	Ahi1^tm1Xjl/Ahi1^tm1Xjl Tg(Nes-cre)1Kln/0	involves: 129 * C57BL/6 * SJL	MGI:4849288

Genotype
MGI:4849288

cn1

• Allelic Composition: Ahi1^tm1Xjl/Ahi1^tm1Xjl; Tg(Nes-cre)1Kln/0
• Genetic Background: involves: 129 * C57BL/6 * SJL

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

behavior/neurological phenotype ( J:166236 )

N • mice do not exhibit increased anxiety in an open field, dark/light box, or elevated plus maze

behavioral despair ( J:166236 )

• at 7 to 9 months and 12 to 15 months, mice spend more time immobile in a forced swim test (FTS) or tail suspension test (TST) than wild-type mice

• mice exhibit less escape activity from a water tank compared with wild-type mice

• however, treatment with antidepressants improves mobility in FTS and TST