All Phenotypes Tg(Fabp4-lacZ)4Mosh MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Tg(Fabp4-lacZ)4Mosh
transgene insertion 4, Moshe Shani
MGI:4849449

Summary

3 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
cn1	Gt(ROSA)26Sor^{tm1(PDGFB)Cbet}/Gt(ROSA)26Sor⁺ Pdgfb^tm1Cbet/Pdgfb^tm1Cbet Tg(Fabp4-lacZ)4Mosh/0 Tg(Tek-cre)1Ywa/0	involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6 * FVB/N * SJL	MGI:4849465
cn2	Gt(ROSA)26Sor^{tm1(PDGFB)Cbet}/Gt(ROSA)26Sor^{tm1(PDGFB)Cbet} Pdgfb^tm1Cbet/Pdgfb^tm1Cbet Tg(Fabp4-lacZ)4Mosh/0 Tg(Tek-cre)1Ywa/0	involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6 * FVB/N * SJL	MGI:4849467
cx3	Pdgfb^tm3.1Cbet/Pdgfb^tm3.1Cbet Tg(Fabp4-lacZ)4Mosh/0	involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * FVB/N	MGI:4849469

Allelic Composition	Gt(ROSA)26Sor^{tm1(PDGFB)Cbet}/Gt(ROSA)26Sor⁺ Pdgfb^tm1Cbet/Pdgfb^tm1Cbet Tg(Fabp4-lacZ)4Mosh/0 Tg(Tek-cre)1Ywa/0
Genetic Background	involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6 * FVB/N * SJL

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gt(ROSA)26Sor^{tm1(PDGFB)Cbet} mutation (0 available); any Gt(ROSA)26Sor mutation (993 available)
Pdgfb^tm1Cbet mutation (0 available); any Pdgfb mutation (15 available)
Tg(Fabp4-lacZ)4Mosh mutation (1 available)
Tg(Tek-cre)1Ywa mutation (6 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

cardiovascular system

abnormal blood vessel morphology ( J:166532 )

• mural cell (pericytes and vascular smooth muscle cells) densities are lower than in wild-type mice

Allelic Composition	Gt(ROSA)26Sor^{tm1(PDGFB)Cbet}/Gt(ROSA)26Sor^{tm1(PDGFB)Cbet} Pdgfb^tm1Cbet/Pdgfb^tm1Cbet Tg(Fabp4-lacZ)4Mosh/0 Tg(Tek-cre)1Ywa/0
Genetic Background	involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6 * FVB/N * SJL

Find Mice

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

cardiovascular system

cardiovascular system phenotype ( J:166532 )

N	• mural cell (pericytes and vascular smooth muscle cells) densities are close to normal

Allelic Composition	Pdgfb^tm3.1Cbet/Pdgfb^tm3.1Cbet Tg(Fabp4-lacZ)4Mosh/0
Genetic Background	involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * FVB/N

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Pdgfb^tm3.1Cbet mutation (0 available); any Pdgfb mutation (15 available)
Tg(Fabp4-lacZ)4Mosh mutation (1 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

cardiovascular system

abnormal blood vessel morphology ( J:166532 )

• mural cell (pericytes and vascular smooth muscle cells) densities are lower than in wild-type mice

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