Analysis Tools|
Allele Symbol Allele Name Allele ID |
Gsk3btm1.1Ypc targeted mutation 1.1, YiPing Chen MGI:4867288 |
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| Summary |
2 genotypes
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
| N |
• unlike germline null mice, mice survive postnatally
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| N |
• unlike in germline null mice, palate formation is normal
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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• at E18.5 anterior shelves are in a horizontal position but fail to meet at the midline; posterior shelves remain in a vertical orientation
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• 11 of 14 mice show complete cleft of the secondary palate
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• at E14.5 the shelves remain in the vertical position and fail to elevate to the position above the tongue
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• at E18.5 anterior shelves are in a horizontal position but fail to meet at the midline; posterior shelves remain in a vertical orientation
|
|
• 11 of 14 mice show complete cleft of the secondary palate
|
|
• at E14.5 the shelves remain in the vertical position and fail to elevate to the position above the tongue
|
|
• at E18.5 anterior shelves are in a horizontal position but fail to meet at the midline; posterior shelves remain in a vertical orientation
|
|
• 11 of 14 mice show complete cleft of the secondary palate
|
|
• at E14.5 the shelves remain in the vertical position and fail to elevate to the position above the tongue
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 12/10/2024 MGI 6.24 |
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