Phenotypes associated with this allele

• Allele Symbol: Tmf1^tm1Unir
• Allele Name: targeted mutation 1, Uri Nir
• Allele ID: MGI:4867389
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Tmf1^tm1Unir/Tmf1^tm1Unir	involves: 129/Sv * ICR	MGI:4867396

Genotype
MGI:4867396

hm1

• Allelic Composition: Tmf1^tm1Unir/Tmf1^tm1Unir
• Genetic Background: involves: 129/Sv * ICR

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

reproductive system

reproductive system phenotype ( J:166798 )

N • female mice exhibit normal fertility

abnormal sperm midpiece morphology ( J:166798 )

♂

abnormal sperm mitochondrial sheath morphology ( J:166798 )

♂

globozoospermia ( J:166798 )

♂

absent acrosome ( J:166798 )

♂

abnormal spermatid morphology ( J:166798 )

♂ • spermatids contain condensed, amorphous, nuclear cargo surrounded by cytoplasmic remnants unlike in wild-type cells

asthenozoospermia ( J:166798 )

♂

decreased testis weight ( J:166798 )

♂

male infertility ( J:166798 )

♂

endocrine/exocrine glands

decreased testis weight ( J:166798 )

♂

cellular

abnormal sperm midpiece morphology ( J:166798 )

♂

abnormal sperm mitochondrial sheath morphology ( J:166798 )

♂

globozoospermia ( J:166798 )

♂

absent acrosome ( J:166798 )

♂

abnormal spermatid morphology ( J:166798 )

♂ • spermatids contain condensed, amorphous, nuclear cargo surrounded by cytoplasmic remnants unlike in wild-type cells

asthenozoospermia ( J:166798 )

♂