Phenotypes associated with this allele

• Allele Symbol: Rp1^tvrm64
• Allele Name: translational vision research model 64
• Allele ID: MGI:4867393
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Rp1^tvrm64/Rp1^tvrm64	C57BL/6J-Rp1^tvrm64/J	MGI:4867826

Genotype
MGI:4867826

hm1

• Allelic Composition: Rp1^tvrm64/Rp1^tvrm64
• Genetic Background: C57BL/6J-Rp1^tvrm64/J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

vision/eye

vision/eye phenotype ( J:166679 )

N • at 1 month of age, dark-adapted ERGs of mutant mice were comparable to controls

abnormal ocular fundus morphology ( J:166679 )

• grainy fundus appearance

abnormal retina vasculature morphology ( J:166679 )

• attenuated retinal vessels

short photoreceptor inner segment ( J:166679 )

• the difference in IS length between mutant and controls is barely discernable at 1 month of age but is obviously shorter at three months of age

short photoreceptor outer segment ( J:166679 )

• the OS length of mutant retina is approximately 50% shorter than controls at 1 month of age

retina photoreceptor degeneration ( J:166679 )

• progressive, with little difference in cell body number in the ONL at 1 month of age but by 3 months, cell nuclei are reduced to ~50% in mutants in comparison to controls

nervous system

short photoreceptor inner segment ( J:166679 )

• the difference in IS length between mutant and controls is barely discernable at 1 month of age but is obviously shorter at three months of age

short photoreceptor outer segment ( J:166679 )

• the OS length of mutant retina is approximately 50% shorter than controls at 1 month of age

retina photoreceptor degeneration ( J:166679 )

• progressive, with little difference in cell body number in the ONL at 1 month of age but by 3 months, cell nuclei are reduced to ~50% in mutants in comparison to controls

cardiovascular system

abnormal retina vasculature morphology ( J:166679 )

• attenuated retinal vessels