Phenotypes associated with this allele

• Allele Symbol: Trpm1^rd15
• Allele Name: retinal degeneration 15
• Allele ID: MGI:4867502
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Trpm1^rd15/Trpm1^rd15	B6.Cg-Trpm1^rd15/BocJ	MGI:7619981
hm2	Trpm1^rd15/Trpm1^rd15	Not Specified	MGI:4867508

Genotype
MGI:7619981

hm1

• Allelic Composition: Trpm1^rd15/Trpm1^rd15
• Genetic Background: B6.Cg-Trpm1^rd15/BocJ

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

vision/eye

abnormal retina outer plexiform layer morphology ( J:346902 )

thin retina outer plexiform layer ( J:346902 )

• at 5 months of age

retina degeneration ( J:346902 )

• by 9 months of age

absent b-wave ( J:346902 )

• although the fundus is normal at 4 weeks of age there is no rod ERG b-wave

abnormal cone electrophysiology ( J:346902 )

• poor cone ERG by 4 weeks of age

abnormal rod electrophysiology ( J:346902 )

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
congenital stationary night blindness 1C		DOID:0110867	OMIM:613216	J:346902

Genotype
MGI:4867508

hm2

• Allelic Composition: Trpm1^rd15/Trpm1^rd15
• Genetic Background: Not Specified

vision/eye

abnormal retina outer plexiform layer morphology ( J:166679 , J:167193 )

• poor histology at 5 months of age (J:167193)

retina degeneration ( J:166679 , J:167193 )

• observed at 9 months of age (J:167193)

abnormal cone electrophysiology ( J:167193 )

• poor cone ERG by 4 weeks of age

abnormal rod electrophysiology ( J:167193 )

• no rod b-wave by 4 weeks of age