Phenotypes associated with this allele

• Allele Symbol: Lsamp^tm1Jinn
• Allele Name: targeted mutation 1, Jurgen Innos
• Allele ID: MGI:4867852
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Lsamp^tm1Jinn/Lsamp^tm1Jinn	involves: 129S6/SvEvTac * C57BL/6	MGI:4867865

Genotype
MGI:4867865

hm1

• Allelic Composition: Lsamp^tm1Jinn/Lsamp^tm1Jinn
• Genetic Background: involves: 129S6/SvEvTac * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

decreased anxiety-related response ( J:166944 )

• under illuminated conditions, mice do not reduce their exploration of an elevated plus-maze unlike wild-type mice

abnormal grooming behavior ( J:166944 )

• before 16 weeks of age, mice lack or exhibit a decrease in barbering and whisker trimming behaviors compared with wild-type mice

impaired swimming ( J:166944 )

• mice are slow swimmers compared with wild-type mice

increased locomotor activity ( J:166944 )

• distance traveled within the first 10 minutes is increased compared with wild-type mice

• however, no significant difference in activity is recorded in the second and third 10 minute period

abnormal social/conspecific interaction behavior ( J:166944 )

• male mice spend less time sniffing the anogenital area of other male mice compared with wild-type mice

decreased aggression towards male mice ( J:166944 )

• male mice do not display aggressive attacks unlike wild-type mice

growth/size/body

decreased body weight ( J:166944 )