Phenotypes associated with this allele

• Allele Symbol: Myo9b^tm1.2Bah
• Allele Name: targeted mutation 1.2, Martin Bahler
• Allele ID: MGI:4867915
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Myo9b^tm1.2Bah/Myo9b^tm1.2Bah	B6.Cg-Myo9b^tm1.2Bah	MGI:4867916

Genotype
MGI:4867916

hm1

• Allelic Composition: Myo9b^tm1.2Bah/Myo9b^tm1.2Bah
• Genetic Background: B6.Cg-Myo9b^tm1.2Bah

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

immune system

decreased leukocyte cell number ( J:162326 )

• accumulation of monocytes and macrophages in the peritoneal cavity of C5a-induced peritonitis model was severely reduced

abnormal macrophage physiology ( J:162326 )

• isolated macrophages failed to spread and polarize in vitro

• isolated macrophage shows defective membrane protrusive activity

• mice have breed normal, and no detailed phenotypic analyses other than that of isolated macrophage were reported

impaired macrophage chemotaxis ( J:162326 )

• isolated macrophage motility and chemotaxis are impaired

hematopoietic system

decreased leukocyte cell number ( J:162326 )

• accumulation of monocytes and macrophages in the peritoneal cavity of C5a-induced peritonitis model was severely reduced

abnormal macrophage physiology ( J:162326 )

• isolated macrophages failed to spread and polarize in vitro

• isolated macrophage shows defective membrane protrusive activity

• mice have breed normal, and no detailed phenotypic analyses other than that of isolated macrophage were reported

impaired macrophage chemotaxis ( J:162326 )

• isolated macrophage motility and chemotaxis are impaired

cellular

impaired macrophage chemotaxis ( J:162326 )

• isolated macrophage motility and chemotaxis are impaired