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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Del(10Prmt2-Cstb)4Yah
deletion, Chr 10, Yann Herault 4
MGI:4868385
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
ht1
Del(10Prmt2-Cstb)4Yah/+ involves: 129P2/OlaHsd * BALB/c * C3H/HeH * C57BL/6 MGI:4868434
cx2
Del(10Prmt2-Cstb)4Yah/+
Tc(HSA21)1TybEmcf/0
involves: 129P2/OlaHsd * BALB/c * C3H/HeH * C57BL/6 MGI:4868435


Genotype
MGI:4868434
ht1
Allelic
Composition
Del(10Prmt2-Cstb)4Yah/+
Genetic
Background
involves: 129P2/OlaHsd * BALB/c * C3H/HeH * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Del(10Prmt2-Cstb)4Yah mutation (1 available); any Del(10Prmt2-Cstb)4Yah mutation (1 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
behavior/neurological
N
• performance on a rotarod similar to controls
• performance on a notched bar test of hindlimb performance is similar to controls
• anxiety measured in an open field test similar to controls




Genotype
MGI:4868435
cx2
Allelic
Composition
Del(10Prmt2-Cstb)4Yah/+
Tc(HSA21)1TybEmcf/0
Genetic
Background
involves: 129P2/OlaHsd * BALB/c * C3H/HeH * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Del(10Prmt2-Cstb)4Yah mutation (1 available); any Del(10Prmt2-Cstb)4Yah mutation (1 available)
Tc(HSA21)1TybEmcf mutation (3 available); any Tc(HSA21)1TybEmcf mutation (4 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
behavior/neurological
• slower to learn task in a Morris Maze test
• travelled further to find the hidden platform
• little retention of learning seen during probe trials in a Morris Maze test
• less time spent in the periphery of an open field test
• perform poorly on a rotarod
• fall of a rotarod more rapidly and at slower speeds
• rotarod performance does not improve with practice
• 25% more errors than controls on a notched bar test of hindlimb performance
• investigation of a newly introduced mouse is normal
• no distinction made between mice after the later introduction of a second new mouse





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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory