Phenotypes associated with this allele

• Allele Symbol: Cstb^tm1Yah
• Allele Name: targeted mutation 1, Yann Herault
• Allele ID: MGI:4868410
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Cstb^tm1Yah/Cstb^tm1Yah	B6.129P2-Cstb^tm1Yah	MGI:5315420
ht2	Cstb^tm1Yah/Cstb^+	B6.129P2-Cstb^tm1Yah	MGI:5315421

Genotype
MGI:5315420

hm1

• Allelic Composition: Cstb^tm1Yah/Cstb^tm1Yah
• Genetic Background: B6.129P2-Cstb^tm1Yah

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

behavior/neurological phenotype ( J:181132 )

N • no signs of ataxia and no difference in distance travelled in open field tests

N • 3rd fall latency on a rotorod is not different in the first 5 sessions or in the 7th session or later

N • no epileptiform abnormalities (seizures or EEG)

N • response to PTZ injection is similar to controls

nervous system

nervous system phenotype ( J:181132 )

N • no signs of cerebral atrophy

N • no change in granule cell layer

Genotype
MGI:5315421

ht2

• Allelic Composition: Cstb^tm1Yah/Cstb⁺
• Genetic Background: B6.129P2-Cstb^tm1Yah

behavior/neurological

behavior/neurological phenotype ( J:181132 )

N • no signs of ataxia and no difference in distance travelled in open field tests

N • 3rd fall latency on a rotorod is not different in the first 5 sessions or in the 7th session or later

N • no epileptiform abnormalities (seizures or EEG)

N • response to PTZ injection is similar to controls

nervous system

nervous system phenotype ( J:181132 )

N • no signs of cerebral atrophy

N • no change in granule cell layer