Analysis Tools
nervous system
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• frequencies of locomotor activity induced in isolated spinal cords increase with increasing NMDA concentrations, but are significantly lower than those observed in control spinal cords
• locomotor burst duration increases but duty cycle is not changed in mutant preparations (increased interburst interval)
• coefficients of variation of main locomotor parameters (cycle period, burst duration, amplitude, duty cycle) are increased compared to controls
• spinal cords from mutants display lower drug-evoked and stimulus-evoked locomotor frequencies
• flexor-extensor coupling is not significantly changed at any locomotor frequency
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