Phenotypes associated with this allele

• Allele Symbol: Kdm1a^{tm1(NCOM)Mfgc}
• Allele Name: targeted mutation 1, Mammalian Functional Genomics Centre
• Allele ID: MGI:4880311
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Kdm1a^tm1(NCOM)Mfgc/Kdm1a^tm1(NCOM)Mfgc	C57BL/6N-Kdm1a^tm1(NCOM)Mfgc/Nju	MGI:5767701
ht2	Kdm1a^tm1(NCOM)Mfgc/Kdm1a^+	C57BL/6N-Kdm1a^tm1(NCOM)Mfgc/Nju	MGI:5757278

Genotype
MGI:5767701

hm1

• Allelic Composition: Kdm1a^{tm1(NCOM)Mfgc}/Kdm1a^{tm1(NCOM)Mfgc}
• Genetic Background: C57BL/6N-Kdm1a^{tm1(NCOM)Mfgc}/Nju
• Cell Lines: N01650P1_C_143W_E7

Data Sources

IMPC Data for Kdm1a

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

preweaning lethality, complete penetrance ( J:211773 )

IMPC - MARC

Genotype
MGI:5757278

ht2

• Allelic Composition: Kdm1a^{tm1(NCOM)Mfgc}/Kdm1a⁺
• Genetic Background: C57BL/6N-Kdm1a^{tm1(NCOM)Mfgc}/Nju
• Cell Lines: N01650P1_C_143W_E7

Data Sources

IMPC Data for Kdm1a

behavior/neurological

decreased grip strength ( J:211773 )

IMPC - MARC

decreased locomotor activity ( J:211773 )

IMPC - MARC

cardiovascular system

small heart ( J:211773 )

♀

IMPC - MARC

hematopoietic system

increased basophil cell number ( J:211773 )

IMPC - MARC

increased eosinophil cell number ( J:211773 )

IMPC - MARC

increased mean platelet volume ( J:211773 )

♂

IMPC - MARC

small spleen ( J:211773 )

♀

IMPC - MARC

immune system

increased basophil cell number ( J:211773 )

IMPC - MARC

increased eosinophil cell number ( J:211773 )

IMPC - MARC

small spleen ( J:211773 )

♀

IMPC - MARC

liver/biliary system

small liver ( J:211773 )

♀

IMPC - MARC

renal/urinary system

small kidney ( J:211773 )

♀

IMPC - MARC

respiratory system

small lung ( J:211773 )

♀

IMPC - MARC