Phenotypes associated with this allele

• Allele Symbol: Calb2^{tm2.1(cre/ERT2)Zjh}
• Allele Name: targeted mutation 2.1, Z Josh Huang
• Allele ID: MGI:4880758
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Calb2^tm2.1(cre/ERT2)Zjh/Calb2^tm2.1(cre/ERT2)Zjh	involves: C57BL/6 * SJL	MGI:4947127
ht2	Calb2^tm2.1(cre/ERT2)Zjh/Calb2^+	involves: C57BL/6 * SJL	MGI:4947128

Genotype
MGI:4947127

hm1

• Allelic Composition: Calb2^{tm2.1(cre/ERT2)Zjh}/Calb2^{tm2.1(cre/ERT2)Zjh}
• Genetic Background: involves: C57BL/6 * SJL

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

impaired coordination ( J:151755 )

• homozygotes are expected to show defects similar to those in mice with null mutations in Calb2, such as impaired motor coordination

nervous system

abnormal nervous system electrophysiology ( J:151755 )

• homozygotes are expected to show defects similar to those in mice with null mutations in Calb2

reduced long-term potentiation ( J:151755 )

• homozygotes are expected to show defects similar to those in mice with null mutations in Calb2, including impaired induction of LTP in the dentate gyrus

Genotype
MGI:4947128

ht2

• Allelic Composition: Calb2^{tm2.1(cre/ERT2)Zjh}/Calb2⁺
• Genetic Background: involves: C57BL/6 * SJL

normal phenotype

no abnormal phenotype detected ( J:151755 )

• mice are viable, fertile, normal in size and do not display any gross physical or behavioral abnormalities