All Phenotypes Fxn<tm1.1Pand> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Fxn^tm1.1Pand
targeted mutation 1.1, Massimo Pandolfo
MGI:4881494

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
ht1	Fxn^tm1.1Pand/Fxn^tm1Mkn	B6.Cg-Fxn^tm1.1Pand Fxn^tm1Mkn/J	MGI:6101473

Allelic Composition	Fxn^tm1.1Pand/Fxn^tm1Mkn
Genetic Background	B6.Cg-Fxn^tm1.1Pand Fxn^tm1Mkn/J

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Fxn^tm1.1Pand mutation (2 available); any Fxn mutation (42 available)
Fxn^tm1Mkn mutation (14 available); any Fxn mutation (42 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

cellular

abnormal mitochondrial biogenesis ( J:242978 )

• mice exhibit a mitochondrial biogenesis defect, with decreases in mitochondrial copy number in brain and skeletal muscle tissue

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
Friedreich ataxia		DOID:12705		J:242978

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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