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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Mylk3tm1Jtst
targeted mutation 1, James Stull
MGI:4881762
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Mylk3tm1Jtst/Mylk3tm1Jtst involves: 129S/SvEv * C57BL/6 MGI:4881768
ht2
Mylk3tm1Jtst/Mylk3+ involves: 129S/SvEv * C57BL/6 MGI:4881769


Genotype
MGI:4881768
hm1
Allelic
Composition
Mylk3tm1Jtst/Mylk3tm1Jtst
Genetic
Background
involves: 129S/SvEv * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mylk3tm1Jtst mutation (0 available); any Mylk3 mutation (42 available)
phenotype observed in females
phenotype observed in males
N normal phenotype

Mylk3tm1Jtst/Mylk3+ and Mylk3tm1Jtst/Mylk3tm1Jtst mice exhibit hypertrophic hearts

cardiovascular system
• in untreated and isoproterenol treated mice
• mice exhibit increased left ventricular end-systolic and end-diastolic dimensions compared with wild-type mice
• in untreated and isoproterenol treated mice
• in the ventricle, but not atria, at 19 to 22 weeks

muscle

growth/size/body

cellular
• in the ventricle, but not atria, at 19 to 22 weeks




Genotype
MGI:4881769
ht2
Allelic
Composition
Mylk3tm1Jtst/Mylk3+
Genetic
Background
involves: 129S/SvEv * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mylk3tm1Jtst mutation (0 available); any Mylk3 mutation (42 available)
phenotype observed in females
phenotype observed in males
N normal phenotype

Mylk3tm1Jtst/Mylk3+ and Mylk3tm1Jtst/Mylk3tm1Jtst mice exhibit hypertrophic hearts





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last database update
10/29/2024
MGI 6.24
The Jackson Laboratory